NATGENE® DNA TEST who is addressed to?
For those of you who are you going to seriously face a preventive way. For those of you who have decided to reprogram and customize the approach to the management of your health and wellness. For those of you who want to lengthen your life, knowing the potentialities and limits of your body. For those of you who want to invest in the health of your children and your grandchildren.
What’s the use? The most recent discoveries about the human genome provide us with bases and tools to understand the sophisticated molecular mechanisms by which individual genes, or their combinations, reply to changes in diet and lifestyle. Ultimately the potentiality of this new approach will introduce a new era, the one of “personalized medicine and lifestyle.”
NATGENE® DNA TEST
It's divided in three sectors: DIET& FOOD - HEALTH & WELLNESS - FITNESS & SPORT . Each of them contains specific test according with your needs. Discover the full range.
You are not an average.
You can create your own method to achieve any kind of goals, both in sport and in ordinary life
Natgene© DNA tests are not comparable to any of genomic services on the national and international market for the following uniqueness:
High number of analyzed genes
Genetic markers selected by an international team of specialists
Personalized medical report compiled by a Medical Geneticist
Multivariate statistical algorithms to increase the predictive power
Accuracy and reproducibility guaranteed by Natgene© protocols
Procedures according to current regulations regarding the genetic testing
To everyone, especially to those who care about their health and, in particular:
To healthy people, who want to learn to know their body with the aim of keeping undamaged their state of health and prevent problems
To sick people, to understand some of the possible genomic causes responsible for their disease state
To agonistic and amateur athletes determined to reach their “optimum” organic, to increase performance and reduce the incidence of injuries (and recovery)
You, your Coach or Medical doctors have a diagnostic tool able to communicate vital information both for healthy people, who decided to maintain their high quality standards of life both for the sick, who decided to find out some causes of diseases and dysfunctions.
A tool that integrates clinical assays, increasing the accuracy of medical diagnosis and understanding unique features of patients
Specialist medical report concerning innovative diagnostic analysis contains five main categories of information:
1. evaluated further (clinical examinations of health status evaluation)
2. indications of foods recommended / to be avoided
3. indications of activities, behaviors and lifestyles
4. directions food integration (active ingredients)
5. Recommended treatments and therapies according to the attending physician Doctor or Coach.
Example test layout Natgene© DNA
This sample we'll show you how to be able to read and interpret as well as possible the genomic data obtained with Natgene© DNA test. In each section (eg. oxidative stress) you can quickly identify gene mutations that we have analysed and you will then be able to get an answer to your questions (outcome). Sections start with:
Summary table of the genomic variants:
Role and/or function It is the effect that the mutation might have on the patient. (eg. protective function against free radicals)
Genotype effect The variant of genotype always has three possible optionsand to these three possibilities an effect on patient health corresponds:
Red circle: the presence of a risk factor
Green circle: the presence of a protective factor
No circle: common variant (or lack of results),
“P”: variant that predisposes for physical power activities (Power) for SportFit test.
“E”: variant that predisposes for physical endurance activity (Endurance) for SportFit test.
The dependent variant of NRF2 gene predisposes the patient to a reduction of defence systems against free radicals and all those substances that can damage the nervous system.
Furthermore, the patient has a genetic variant (APOE) that may predispose to the development of neurodegenerative diseases.
Recommended diagnostic examinations
Cortisol (24 h urine)
Hydroxycorticosteroids-ketosteroidi (24 h urine)
DHEA, melatonin and cortisol (saliva)
Below the so called GS,Genotype score, which will allow to identify the level of prevention to which the patient should undergo. In this case there are four possible levels of prevention:
Blue band: below average, no special preventive measures
Green band: above average, decreases considerably prevention
Yellow band: between one and two standard deviations, implement a preventive path
Red band: more than two standard deviations, decided to implement a prevention course In all prevention levels above you should consult your doctor to identify the best possible strategy
Based on the analysed genomic data, it is recommended to the patient to implement a series of actions to reduce the phenomena of oxidative stress:
Vitamin E .
Recommended nutritional supplementation
Based on the analysed genomic data, the patient does not need a particular nutritional integration path.
Recommended behaviours or lifestyles
Based on the analysed genomic data, it is recommended to the patient to put into practice all the possible strategies for stress reduction. If it is deemed necessary, given all the other parameters not considered in this test, it is advisable to agree with doctor the most appropriate strategy to the treatment of symptoms. In order to promote the free radical protection, it is recommended to the patient to avoid smoking, limit the use of drugs (especially antibiotics) if possible and avoid exposure so unprotected to sunlight.
Based on the analysed genomic data, the patient does not require any specific treatment.
Quality management systems
General requirements for the competence of testing and calibration laboratories
Tecnology and automation
MIUR award for human, animal and plant genotyping
Laboratory Information Management System
In collaboration with LIFE Technologies Corporation
In Vitro Diagnostic Medical Devices
Validation and Method
Quality Control (QC) for reproducibility assessment
European Society of Human Genetics (ESHG)
In accordance with the guidelines for genetic testing
Technological District of Life Sciences
Toscana Life Science (TLS) Tuscany Region